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Botanical Drug Research & Development

Paper Submission

Print ISSN: 2578-7047 | Online SSN: 2578-7055

Medicinal plant-based saponins targeting COVID-19 Mpro in silico

Abstract Background: Recently, the Chinese scientists Liu et al. demonstrated a crystallized form of severe acute respiratory syndrome...

Traditional medicine on tumor immunity regulation

Possible anticancer cachexia effects of the main active compounds of Radix Sophorae flavescentis

TCM's Effect on Anxiety Tested in Randomized Controlled Trial

Effects of processing technology on essential oil and pharmacological action of frankincense

Panax notoginseng saponins' modulation of cerebrovascular

Herb Exocarpium Citri grandis in the prevention and treatment of COVID-19

Abstract Huajuhong (Exocarpium Citri grandis, ECG) is a traditional Chinese herbal medicine and has been used for the treatment of...

Complementary and alternative medicine applications in cancer medicine

Abstract Besides conventional medicine, many patients with cancer seek complementary and alternative medicine (CAM) as an additional...

Mechanism of Xiaoxianxiong Decoction for type 2 diabetes Mellitus

Background: Xiaoxianxiong decoction is a classic formula in traditional Chinese medicine used to treat type 2 diabetes mellitus and...

Danggui Buxue decoction promotes proliferation of Caco-2 cells and antagonizes obesity

Background: Chinese medicine has been proposed as a novel approach to the prevention of metabolic disorders such as obesity. Danggui...

Chlorogenic acid may be a potent inhibitor of dimeric SARS-CoV-2 main protease 3CLpro

Abstract Background: Since the emergence of coronavirus disease 2019 to date, there is no available approved drug or definitive treatment...

Modelling Bioactivities of Botanical Extracts Using Network Pharmacology and Polypharmacology.

ABSTRACT: Network pharmacology and polypharmacology are emerging as novel drug discovery paradigms. The many discovery, safety and...

Botanical drug clinical trial: common issues and future options

ABSTRACT Botanical drugs are plant-derived, complex mixtures which may have synergistic effects. In order to understand this disparity...

The Development of Botanical Drugs – A Review

Plants for millennia have provided the major source of the medicinal compounds used to treat our illnesses. Until the early 1900’s...

Botanical Drug Development and Quality Standards

The Center for Drug Evaluation and Research (CDER) established the Botanical Review Team in 2003, published a Guidance for Industry:...

EU regulatory and Quality Requirements for Botanical Drugs and Their Implications

European Union regulatory and quality requirements for botanical drugs and their implications for Chinese herbal medicinal products...

Development and Validation of In-line Near-Infrared Spectroscopy Based Analytical Method

Development and validation of in-line near-infrared spectroscopy based analytical method for commercial production of a botanical drug...

Multiple chromatographic fingerprinting and its application to the quality control of herbal medicin

Abstract Recently, chromatographic fingerprinting has become one of the most powerful approaches to quality control of herbal medicines....

AUTHENTICATION AND QUALITY ASSESSMENT OF BOTANICALS AND BOTANICAL PRODUCTS USED IN CLINICAL RESEARCH

Abstract: Fundamental in the clinical assessment of herbal drugs is the need for the full characterization of the botanical and/or the...

Botanical Drug Development: Waiver of Preclinical Pharm/Tox Studies and Importance of Initial Clinic

Abstract Development of botanical drug products in the U.S. may be entitled for a waiver of preclinical Pharm/Tox (P/T) studies prior to...

Challenges and recommendations for assessing absorption, distribution, metabolism and excretion

Abstract Botanical dietary supplements are complex mixtures containing one or more botanical ingredient(s), each containing numerous...

Botanical New Drugs: From INDs to NDAs

Botanical mixtures, although many widely used around the world for various health care purposes, have, for the most part, not been...

Botanicals in Dermatology: Essential Oils, Botanical Allergens, and Current Regulatory Practices

Abstract Largely because of their perceived safety, the use of essential oils and other botanically derived products has become...

Merging Traditional Chinese Medicine with Modern Drug Discovery Technologies to Find Novel Drugs

Traditional Chinese Medicines (TCM) are rapidly gaining attention in the West as sources of new drugs, dietary supplements and functional...