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ReHeva Biosciences, a biopharmaceutical startup helping people live longer and healthier with cancer through botanically-derived complex drugs, is announcing the first patient enrolled and dosed in the Phase I Safety Trial for the company's drug, RH324. This Trial is being conducted in advanced non-small cell lung cancer (NSCLC) patients at University Hospitals in Cleveland.

"At ReHeva, we do not accept that unwanted side effects and brief remission periods are an inevitable part of cancer treatment. Our transformative approach targeting multiple tissues and mechanisms of action through botanically-derived agents addresses an unmet need and opportunity to develop drugs that treat major diseases with long term safety, efficacy, and affordability," said Dr. Zeenia Kaul, CEO, Co-Founder and Chief Scientific Officer of ReHeva. "The first patients enrolled in our Phase I Safety Trial is an exciting step in making our mission a reality."

This clinical study addresses the safety and tolerability of three dose levels of RH324 in patients with advanced NSCLC who take RH324 twice daily for 28 days. The study should be completed by end of 2022.

Founded in 2016 by Kaul, ReHeva is built on more than 20 years of pre-clinical research and development and supported by studies published in highly regarded peer-reviewed journals.

ReHeva received FDA Investigational New Drug allowance (IND) in 2018 to conduct Phase I Safety Study in advanced NSCLC patients. ReHeva's approach relies on the multifaceted and broad-spectrum benefits of RH324, allowing it to have a positive effect on a multitude of pathways involved in cancer.


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